Article
Natural killer (NK) cell receptors' repertoire in couples with recurrent spontaneous abortions.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2003
Varla-Leftherioti Marighoula, Spyropoulou-Vlachou Maria, Niokou Demetra, Keramitsoglou Theodora, Darlamitsou Areti, Tsekoura Christina, Papadimitropoulos Miltiadis, Lepage Virginia, Balafoutas Christos, Stavropoulos-Giokas Catherine
Abstract excerpt
PROBLEM: Natural killer (NK) cell receptors (NKRs) have been suggested to protect trophoblast, but their function at the fetomaternal interface remains unknown. To investigate if the outcome of pregnancy depends on women's NKRs, we studied the NKR repertoire in couples with recurrent spontaneous abortions (RSA). METHODS: Twenty-six childless couples with > or = 2 abortions, characterized by alloimmune...
Topics
- Abortion, Habitual
- Antigens, CD
- Family Characteristics
- Female
- Genotype
- HLA Antigens
- Histocompatibility Antigens Class I
- Humans
- Killer Cells, Natural
- Lectins, C-Type
- Male
- NK Cell Lectin-Like Receptor Subfamily C