Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells.

doi:10.1095/biolreprod.107.062851

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Article

Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells.

Biology of reproduction - 1 Oct 2007

Iwahashi Kazuhiro, Yoshioka Hirotaka, Low Eleanor W, McCarrey John R, Yanagimachi Ryuzo, Yamazaki Yukiko

Abstract excerpt

In mice, unique events regulating epigenetic programming (e.g., genomic imprinting) and replication state (mitosis versus meiosis) occur during fetal germ cell development. To determine whether these processes are autonomously programmed in fetal germ cells or are dependent upon ongoing instructive interactions with surrounding gonadal somatic cells, we isolated male and female germ cells at 13.5 days postcoitum...

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PMID: 17615405
DOI: 10.1095/biolreprod.107.062851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.