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Article

F8 gene mutation profile and ITT response in a cohort of Italian haemophilia A patients with inhibitors.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2007

Salviato R, Belvini D, Radossi P, Sartori R, Pierobon F, Zanotto D, Zanon E, Castaman G, Gandini G, Tagariello G

Abstract excerpt

Anti factor VIII (FVIII) antibodies represent the main complication of replacement therapy in severe cases of haemophilia and most patients with inhibitor have gross gene rearrangements or point mutations that hamper the production of normal circulating FVIII. In this study we have investigated 82 haemophilia A patients with inhibitors. Seventy six were severe, three were moderate and three were mild. We screened...

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Identifiers

PMID: 17610549
DOI: 10.1111/j.1365-2516.2007.01437.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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