Article
Factor 8 (F8) gene mutation profile of Turkish hemophilia A patients with inhibitors.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2008
Fidanci Inanç D, Kavakli Kaan, Uçar Canan, Timur Cetin, Meral Adalet, Kilinç Yurdanur, Sayilan Hülya, Kazanci Elif, Cağlayan S Hande
Abstract excerpt
Factor VIII (FVIII) replacement therapy is ineffective in hemophilia A patients who develop alloantibodies (inhibitors) against FVIII. The type of factor 8 (F8) gene mutation, genes in the major histocompatibility complex loci, and also polymorphisms in IL-10 and tumor necrosis factor-alpha are t...
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