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Atomoxetine pharmacokinetics in healthy Chinese subjects and effect of the CYP2D6*10 allele

4 Jul 2007

Abstract excerpt

What is already known about this subject • Atomoxetine is a cytochrome P450 2D6 (CYP2D6) substrate and its pharmacokinetics has been characterized in a predominantly White population during clinical development. • There are scant East Asian pharmacokinetic data available. • The CYP2D6*10 allele is particularly prevalent in East Asian populations and may contribute to the known ethnic differences in CYP2D6...

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PMID: 17610534
DOI: 10.1111/j.1365-2125.2007.02912.x

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