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Article

Genetic analysis of genes GSTP1, PTEN, and TP53 SNPs in non-melanoma skin cancer patients.

Journal of cancer research and clinical oncology - 12 May 2026

Xiong Yongzhong, Akhter Haider Ali, Siddique Aqsa, Smerat Aseel, Egamberdiyev Kuvonchbek, Gulsara Ruziyeva, Bashir Kashif

Abstract excerpt

BACKGROUND AND OBJECTIVE: One of the most prevalent cancers in the world, non-melanoma skin cancer (NMSC) is impacted by several genetic, demographic, and environmental factors. METHODOLOGY: This case-control study examined the relationship between NMSC susceptibility and GSTP1 (rs1695), PTEN (rs701848), and TP53 (rs17878362) polymorphisms in 300 Pakistani patients and 300 healthy controls. Additionally assessed...

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Share to Aged
Share to Case-Control Studies
Share to Genetic Predisposition to Disease
Share to Glutathione S-Transferase pi
Share to Polymorphism, Single Nucleotide
Share to PTEN Phosphohydrolase
Share to Skin Neoplasms
Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 42118341
DOI: 10.1007/s00432-026-06502-z
PMCID: PMC13338088

Genes

GSTP1
PTEN
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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