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Article

Role of glutathione S-transferases in melanoma susceptibility: association with GSTP1 rs1695 polymorphism.

The British journal of dermatology - 1 Jun 2012

Ibarrola-Villava M, Martin-Gonzalez M, Lazaro P, Pizarro A, Lluch A, Ribas G

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GSTs) GSTM1, GSTT1 and GSTP1 are multifunctional enzymes involved in the detoxification of a wide range of reactive oxygen species produced during melanin synthesis and oxidative stress processes. OBJECTIVES: Single nucleotide polymorphisms (SNPs) in GSTP1 and copy number variants in GSTM1 and GSTT1 may be candidate low-penetrance variants with a role in susceptibility to...

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Source

Identifiers

PMID: 22251241
DOI: 10.1111/j.1365-2133.2012.10831.x

Genes

GSTP1
GSTM1
GSTT1

Variants

rs1695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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