Article
Rot1 plays an antagonistic role to Clb2 in actin cytoskeleton dynamics throughout the cell cycle.
Journal of cell science - 15 Jul 2007
Juanes M Angeles, Queralt Ethel, Bañó M Carmen, Igual J Carlos
Abstract excerpt
ROT1 is an essential gene whose inactivation causes defects in cell cycle progression and morphogenesis in budding yeast. Rot1 affects the actin cytoskeleton during the cell cycle at two levels. First, it is required for the maintenance of apical growth during bud growth. Second, Rot1 is necessary to polarize actin cytoskeleton to the neck region at the end of mitosis; because of this defect, rot1 cells do not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
