Article
Rot1p of Saccharomyces cerevisiae is a putative membrane protein required for normal levels of the cell wall 1,6-beta-glucan.
Microbiology (Reading, England) - 1 Oct 2004
Machi Kazuki, Azuma Masayuki, Igarashi Koichi, Matsumoto Takeshi, Fukuda Hideki, Kondo Akihiko, Ooshima Hiroshi
Abstract excerpt
Although ROT1 is essential for growth of Saccharomyces cerevisiae strain BY4741, the growth of a rot1Delta haploid was partially restored by the addition of 0.6 M sorbitol to the growth medium. Rot1p is predicted to contain 256 amino acids, to have a molecular mass of 29 kDa, and to possess a transmembrane domain near its C-terminus. Candida albicans and Schizosaccharomyces pombe have Rot1p homologues with high...
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