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Article

Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly.

BMC structural biology - 2 Jul 2007

Schormann Norbert, Grigorian Alexei, Samal Alexandra, Krishnan Raman, DeLucas Lawrence, Chattopadhyay Debasish

Abstract excerpt

BACKGROUND: Uracil-DNA glycosylases (UDGs) catalyze excision of uracil from DNA. Vaccinia virus, which is the prototype of poxviruses, encodes a UDG (vvUDG) that is significantly different from the UDGs of other organisms in primary, secondary and tertiary structure and characteristic motifs. It adopted a novel catalysis-independent role in DNA replication that involves interaction with a viral protein, A20, to...

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Source

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Identifiers

PMID: 17605817
DOI: 10.1186/1472-6807-7-45
PMCID: PMC1936997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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