Article
CCL3L1 copy number and susceptibility to malaria.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2012
Carpenter Danielle, Färnert Anna, Rooth Ingegerd, Armour John A L, Shaw Marie-Anne
Abstract excerpt
Copy number variation can contribute to the variation observed in susceptibility to complex diseases. Here we present the first study to investigate copy number variation of the chemokine gene CCL3L1 with susceptibility to malaria. We present a family-based genetic analysis of a Tanzanian population (n=922), using parasite load, mean number of clinical infections of malaria and haemoglobin levels as phenotypes....
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