Article
A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
BMC genetics - 2 Jul 2007
Harris Sarah E, Fox Helen, Wright Alan F, Hayward Caroline, Starr John M, Whalley Lawrence J, Deary Ian J
Abstract excerpt
BACKGROUND: Non-pathological cognitive ageing is a distressing condition affecting an increasing number of people in our 'ageing society'. Oxidative stress is hypothesised to have a major role in cellular ageing, including brain ageing. RESULTS: Associations between cognitive ageing and 325 single nucleotide polymorphisms (SNPs), located in 109 genes implicated in oxidative stress and/or cognition, were examined...
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