Article
Six genetically linked mutations in the CD36 gene significantly delay the onset of Alzheimer's disease.
Scientific reports - 29 Jun 2022
Šerý Omar, Zeman Tomáš, Sheardová Kateřina, Vyhnálek Martin, Marková Hana, Laczó Jan, Lochman Jan, Kralik Petr, Vrzalová Kamila, Dziedzinska Radka, Balcar Vladimir J, Hort Jakub
Abstract excerpt
The risk of Alzheimer's disease (AD) has a strong genetic component, also in the case of late-onset AD (LOAD). Attempts to sequence whole genome in large populations of subjects have identified only a few mutations common to most of the patients with AD. Targeting smaller well-characterized groups of subjects where specific genetic variations in selected genes could be related to precisely defined psychological...
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