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Article

Genetic influences on oxidative stress and their association with normal cognitive ageing.

Neuroscience letters - 30 Sept 2005

Kachiwala Swati J, Harris Sarah E, Wright Alan F, Hayward Caroline, Starr John M, Whalley Lawrence J, Deary Ian J

Abstract excerpt

Oxidative stress is hypothesised to play a major role in ageing processes. Reactive oxygen species produced during normal aerobic metabolism damage cellular macromolecules. The brain is particularly susceptible to oxidative stress due to its high rate of aerobic metabolism. We hypothesised that polymorphisms in genes contributing to antioxidant defences are associated with variation in normal cognitive ageing in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16023289
DOI: 10.1016/j.neulet.2005.05.067

Genes

PRNP
LTF

Variants

rs2073495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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