Article
Natural selection favors a newly derived timeless allele in Drosophila melanogaster.
Science (New York, N.Y.) - 29 Jun 2007
Tauber Eran, Zordan Mauro, Sandrelli Federica, Pegoraro Mirko, Osterwalder Nicolò, Breda Carlo, Daga Andrea, Selmin Alessandro, Monger Karen, Benna Clara, Rosato Ezio, Kyriacou Charalambos P, Costa Rodolfo
Abstract excerpt
Circadian and other natural clock-like endogenous rhythms may have evolved to anticipate regular temporal changes in the environment. We report that a mutation in the circadian clock gene timeless in Drosophila melanogaster has arisen and spread by natural selection relatively recently in Europe. We found that, when introduced into different genetic backgrounds, natural and artificial alleles of the timeless gene...
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