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Article

Flies, clocks and evolution.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Nov 2001

Rosato E, Kyriacou C P

Abstract excerpt

The negative feedback model for gene regulation of the circadian mechanism is described for the fruitfly, Drosophila melanogaster. The conservation of function of clock molecules is illustrated by comparison with the mammalian circadian system, and the apparent swapping of roles between various canonical clock gene components is highlighted. The role of clock gene duplications and divergence of function is...

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Identifiers

PMID: 11710984
DOI: 10.1098/rstb.2001.0961
PMCID: PMC1088553

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