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Article

Opposing roles of C/EBPbeta and AP-1 in the control of fibroblast proliferation and growth arrest-specific gene expression.

The Journal of biological chemistry - 31 Oct 2003

Gagliardi Mark, Maynard Scott, Miyake Tetsuaki, Rodrigues Natalie, Tjew Sie Lung, Cabannes Eric, Bedard Pierre-Andre

Abstract excerpt

Chicken embryo fibroblasts (CEF) express several growth arrest-specific (GAS) gene products in G0. In contact-inhibited cells, the expression of the most abundant of these proteins, the p20K lipocalin, is activated at the transcriptional level by C/EBPbeta. In this report, we describe the role of C/EBPbeta in CEF proliferation. We show that the expression of a dominant negative mutant of C/EBPbeta (designated...

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Identifiers

PMID: 12896981
DOI: 10.1074/jbc.M304085200

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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