Article
Phenotypic properties resulting from directed gene segment reassortment between wild-type A/Sydney/5/97 influenza virus and the live attenuated vaccine strain.
Virology - 25 Oct 2007
Parks Christopher L, Latham Theresa, Cahill Adriana, O'neill Robert E, Passarotti Christopher J, Buonagurio Deborah A, Bechert Thomas M, D'Arco Gail A, Neumann Gabriele, Destefano Joanne, Arendt Heather E, Obregon Jennifer, Shutyak Leonid, Hamm Stefan, Sidhu Mohinderjit S, Zamb Timothy J, Udem Stephen A
Abstract excerpt
Widespread use of a live-attenuated influenza vaccine (LAIV) in the United States (licensed as FluMist) raises the possibility that vaccine viruses will contribute gene segments to the type A influenza virus gene pool. Progeny viruses possessing new genotypes might arise from genetic reassortment between circulating wild-type (wt) and vaccine strains, but it will be difficult to predict whether they will be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.