Article
The effect of lopinavir/ritonavir on the renal clearance of tenofovir in HIV-infected patients.
Clinical pharmacology and therapeutics - 1 Feb 2008
Kiser J J, Carten M L, Aquilante C L, Anderson P L, Wolfe P, King T M, Delahunty T, Bushman L R, Fletcher C V
Abstract excerpt
We determined the effects of lopinavir/ritonavir on tenofovir renal clearance. Human immunodeficiency virus-infected subjects taking tenofovir disoproxil fumarate (TDF) were matched on age, race, and gender and were enrolled into one of the following two groups: group 1: subjects taking TDF plus lopinavir/ritonavir plus other nucleoside reverse transcriptase inhibitors (NRTIs); group 2: subjects taking TDF plus...
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