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Article

The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.

PloS one - 27 Jun 2007

Zhang Shiping, McCormack Francis X, Levesque Roger C, O'Toole George A, Lau Gee W

Abstract excerpt

Surfactant protein A (SP-A) is an important lung innate immune protein that kills microbial pathogens by opsonization and membrane permeabilization. We investigated the basis of SP-A-mediated pulmonary clearance of Pseudomonas aeruginosa using genetically-engineered SP-A mice and a library of signature-tagged P. aeruginosa mutants. A mutant with an insertion into flgE, the gene that encodes flagellar hook...

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Share to Phagocytosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages, Alveolar

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Source

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Identifiers

PMID: 17593964
DOI: 10.1371/journal.pone.0000564
PMCID: PMC1891440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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