Article
Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides.
The Biochemical journal - 15 Oct 1994
Van Iwaarden J F, Pikaar J C, Storm J, Brouwer E, Verhoef J, Oosting R S, van Golde L M, van Strijp J A
Abstract excerpt
Surfactant protein A (SP-A) enhances the phagocytosis of opsonized and non-opsonized bacteria by alveolar macrophages, but it is not known with which component of the bacterial surface it associates. We investigated the interaction of SP-A with lipopolysaccharides (LPS), which are important biologically active constituents of the outer membranes of Gram-negative bacteria. Flow cytometry was used to study the...
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