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Article

Age‐related penetrance of endocrine tumours in multiple endocrine neoplasia type 1 (MEN1): a multicentre study of 258 gene carriers

30 May 2007

Abstract excerpt

OBJECTIVE: In multiple endocrine neoplasia type 1 (MEN1), age-related tumour penetrance according to the type of MEN1 germline mutation has not been investigated in-depth. This study was conducted to examine whether carriers of out-of-frame/truncating and in-frame MEN1 mutations differ in age-related tumour penetrance. DESIGN: A multicentre study with biochemical, hormonal and radiological screening for...

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PMID: 17590169
DOI: 10.1111/j.1365-2265.2007.02934.x

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