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Article

The Ebola Virus VP35 Protein Is a Suppressor of RNA Silencing

18 Jun 2007

Abstract excerpt

RNA silencing or interference (RNAi) is a gene regulation mechanism in eukaryotes that controls cell differentiation and developmental processes via expression of microRNAs. RNAi also serves as an innate antiviral defence response in plants, nematodes, and insects. This antiviral response is triggered by virus-specific double-stranded RNA molecules (dsRNAs) that are produced during infection. To overcome...

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PMID: 17590081
DOI: 10.1371/journal.ppat.0030086

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