Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy.

doi:10.1111/j.1600-0609.2004.00381.x

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Article

Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy.

European journal of haematology - 1 Mar 2005

Sanchaisuriya Kanokwan, Chunpanich Sunisa, Fucharoen Supan, Fucharoen Goonnapa, Sanchaisuriya Pattara, Changtrakun Yossombat

Abstract excerpt

Hemoglobin (Hb) Q-Thailand [alpha74(EF3): Asp-->His] is an abnormal Hb found mainly in China and South-east Asian countries. Association of the alpha(Q-Thailand) allele with alpha-thalassemia has important implications in diagnosis. We report the hitherto undescribed conditions of this variant in two unrelated pregnant Thai women. Routine Hb analyses using high-performance liquid chromatography identified...

Topics

Adult
Chromatography, High Pressure Liquid
DNA Mutational Analysis
Family Health
Female
Genotype
Globins
Hemoglobin E
Hemoglobins, Abnormal
Heterozygote
Homozygote
Humans
Inheritance Patterns
Mutation
Pregnancy
Thailand

Source

Open in PubMed

Identifiers

PMID: 15693792
DOI: 10.1111/j.1600-0609.2004.00381.x

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