Article
Hematological Characteristics of Hb Constant Spring (HBA2: c.427T>C) Carriers in Mainland China.
Hemoglobin - 1 Mar 2020
Jiang Fan, Xu Li-Li, Chen Gui-Lan, Zhou Jian-Ying, Li Jian, Tang Xue-Wei, Zuo Lian-Dong, Li Dong-Zhi
Abstract excerpt
Hb Constant Spring (Hb CS) (HBA2: c.427T>C) is a common α-globin variant causing α-thalassemia (α-thal) phenotypes in mainland China. In this study, we evaluated the efficiency of erythrocyte parameters and capillary electrophoresis (CE) in the determination of Hb CS in blood samples from Hb CS carriers. Based on molecular diagnosis, there were 462 patients carrying Hb CS: 411 Hb CS heterozygotes, seven carried...
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