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Article

Molecular characterization and origins of Hb Constant Spring and Hb Paksé in Southeast Asian populations.

Annals of hematology - 1 Sept 2007

Singsanan Sanita, Fucharoen Goonnapa, Savongsy Onekham, Sanchaisuriya Kanokwan, Fucharoen Supan

Abstract excerpt

Hemoglobin Constant Spring (Hb CS) and Hb Paksé, two abnormal Hbs characterized by elongated alpha-globin chains resulting from mutations of the termination codon in the alpha2-globin gene, are the most prevalent nondeletional alpha-thalassemias in Southeast Asia. To determine the origins of these two variants in the region, we have determined alpha-globin gene haplotypes associated with these two variants on 120...

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PMID: 17589844
DOI: 10.1007/s00277-007-0310-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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