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Article

Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plague.

Cellular microbiology - 1 Nov 2007

Erickson David L, Waterfield Nicholas R, Vadyvaloo Viveka, Long Daniel, Fischer Elizabeth R, Ffrench-Constant Richard, Hinnebusch B Joseph

Abstract excerpt

Yersinia pestis diverged from Yersinia pseudotuberculosis</= 20 000 years ago, during which time it evolved to be transmitted by fleas. In comparing the ability of these closely related species to infect the rat flea Xenopsylla cheopis, we found that Y. pseudotuberculosis, unlike Y. pestis, is orally toxic to fleas. Fleas showed signs of acute toxicity, including diarrhoea, immediately after feeding on blood...

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Identifiers

PMID: 17587333
DOI: 10.1111/j.1462-5822.2007.00986.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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