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Article

Retracing the evolutionary path that led to flea-borne transmission of Yersinia pestis.

Cell host & microbe - 14 May 2014

Sun Yi-Cheng, Jarrett Clayton O, Bosio Christopher F, Hinnebusch B Joseph

Abstract excerpt

Yersinia pestis is an arthropod-borne bacterial pathogen that evolved recently from Yersinia pseudotuberculosis, an enteric pathogen transmitted via the fecal-oral route. This radical ecological transition can be attributed to a few discrete genetic changes from a still-extant recent ancestor, thus providing a tractable case study in pathogen evolution and emergence. Here, we determined the genetic and...

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Identifiers

PMID: 24832452
DOI: 10.1016/j.chom.2014.04.003
PMCID: PMC4084870

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Source receipt: pubmed, retrieved 7 Sept 2026.

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