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Article

Mutation in the pla gene of Yersinia pestis alters the course of the plague bacillus-flea (Siphonaptera: Ceratophyllidae) interaction.

Journal of medical entomology - 1 Jul 1993

McDonough K A, Barnes A M, Quan T J, Montenieri J, Falkow S

Abstract excerpt

Yersinia pestis possesses a unique gene (pla) encoding coagulase and fibrinolysin which is implicated in the transmission of plague by fleas. This gene is encoded on the highly conserved but poorly characterized 'pesticin' plasmid pKYP1. The role of the pKYP1-encoded gene, pla, in plague transmis...

Topics

Animals
Bacterial Proteins
Feeding Behavior
Host-Parasite Interactions
Insect Vectors
Mutagenesis, Insertional
Mutation
Plague
Plasminogen Activators
Siphonaptera
Virulence
Yersinia pestis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8360901
DOI: 10.1093/jmedent/30.4.772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8360901-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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