Article
Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector.
Science (New York, N.Y.) - 26 Apr 2002
Hinnebusch B Joseph, Rudolph Amy E, Cherepanov Peter, Dixon Jack E, Schwan Tom G, Forsberg Ake
Abstract excerpt
Transmission by flea bite is a relatively recent adaptation that distinguishes Yersinia pestis, the plague bacillus, from closely related enteric bacteria. Here, a plasmid-encoded phospholipase D (PLD), previously characterized as Yersinia murine toxin (Ymt), was shown to be required for survival of Y. pestis in the midgut of its principal vector, the rat flea Xenopsylla cheopis. Intracellular PLD activity...
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