Article
Association analysis of brain-derived neurotrophic factor gene polymorphisms in asthmatic children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jun 2007
Szczepankiewicz Aleksandra, Breborowicz Anna, Skibińska Maria, Wiłkość Monika, Tomaszewska Marta, Hauser Joanna
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been described to modulate airway hyper-responsiveness and inflammation and was involved in late allergic reaction in asthma and higher levels of circulating BDNF were present in allergic asthmatics. In BDNF gene, Val66Met and C-270T polymorphisms were described. There were, however, very few studies analyzing BDNF gene polymorphisms in asthma. The aim of this study...
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