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Article

The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site.

Molecular pharmacology - 1 Sept 2007

Patana Anne-Sisko, Kurkela Mika, Goldman Adrian, Finel Moshe

Abstract excerpt

UDP-glucuronosyltransferases (UGTs) play important roles in the metabolism, detoxification,and clearance of many different xenobiotics, including drugs and endogenous compounds. Structural information about these membrane-bound enzymes of the endoplasmic reticulum is limited. We do not know the identity or the location of the key residues for catalysis and binding of the aglycone substrate and the cosubstrate...

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Identifiers

PMID: 17578897
DOI: 10.1124/mol.107.036871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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