Article
Association of HSP70-hom genetic variant with prostate cancer risk.
Molecular biology reports - 1 Sept 2008
Sfar Sana, Saad Hamadi, Mosbah Faouzi, Chouchane Lotfi
Abstract excerpt
Because of the importance of androgens to prostate cancer (PCa) development, several candidate genes along androgen pathway have been under intensive study. Given the role of the molecular chaperone HSP70 in the regulation of the androgen receptor (AR) transactivation function, we first chose to explore the association between the HSP70-hom functional genetic variant (+2437 T > C) and prostate cancer risk by...
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