Article
Association of genetic polymorphisms in vitamin D receptor gene and susceptibility to sporadic prostate cancer.
Experimental biology and medicine (Maywood, N.J.) - 1 Dec 2008
Onen Ilke Hacer, Ekmekci Abdullah, Eroglu Muzaffer, Konac Ece, Yesil Suleyman, Biri Hasan
Abstract excerpt
Genetic and environmental factors are involved in prostate cancer (PCa) etiology. Single nucleotide polymorphisms (SNPs) may contribute to the PCa pathogenesis. The goal of this study is to determine the role of vitamin D receptor (VDR) gene polymorphisms and haplotypes in the development and progression of sporadic PCa. One hundred and thirty-three PCa patients and 157 age-matched healthy controls were genotyped...
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