New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells.

doi:10.1182/blood-2007-05-088443

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New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells.

Blood - 1 Oct 2007

Pérez-Persona Ernesto, Vidriales María-Belén, Mateo Gema, García-Sanz Ramón, Mateos Maria-Victoria, de Coca Alfonso García, Galende Josefina, Martín-Nuñez Guillermo, Alonso José M, de Las Heras Natalia, Hernández José M, Martín Alejandro, López-Berges Consuelo, Orfao Alberto, San Miguel Jesús F

Abstract excerpt

Monoclonal gammopathy of uncertain significance (MGUS) and smoldering multiple myeloma (SMM) are plasma cell disorders with a risk of progression of approximately 1% and 10% per year, respectively. We have previously shown that the proportion of bone marrow (BM) aberrant plasma cells (aPCs) within the BMPC compartment (aPC/BMPC) as assessed by flow cytometry (FC) contributes to differential diagnosis between MGUS...

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PMID: 17576818
DOI: 10.1182/blood-2007-05-088443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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