Article
Methylenetetrahydrofolate reductase (MTHFR) is associated with ovarian follicular activity.
Fertility and sterility - 1 Sept 2007
Rosen Mitchell P, Shen Shehua, McCulloch Charles E, Rinaudo Paolo F, Cedars Marcelle I, Dobson Anthony T
Abstract excerpt
OBJECTIVE: Polymorphisms in the MTHFR gene have been associated with decreased cell division and apoptosis. This finding led us to evaluate whether MTHFR polymorphisms were associated with follicular growth within the ovary. More specifically, we investigated the effect of the two common polymorphisms C677T and A1298C in our population of women undergoing ovarian stimulation. DESIGN: Prospective cohort study....
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