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Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension

13 Oct 2010

Abstract excerpt

BACKGROUND: The prevalence of diabetes is increasing worldwide. It has been long known that increased rates of inflammatory diseases, such as obesity (OBS), hypertension (HT) and cardiovascular diseases (CVD) are highly associated with type 2 diabetes (T2D). T2D and/or OBS can develop independently, due to genetic, behavioral or lifestyle-related variables but both lead to oxidative stress generation. The...

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PMID: 20942928
DOI: 10.1186/1755-8794-3-45

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