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Article

Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.

PloS one - 7 Dec 2009

Sengupta Urmi, Ukil Sanchaita, Dimitrova Nevenka, Agrawal Shipra

Abstract excerpt

Type 2 diabetes mellitus (T2D) is a multifactorial and genetically heterogeneous disease which leads to impaired glucose homeostasis and insulin resistance. The advanced form of disease causes acute cardiovascular, renal, neurological and microvascular complications. Thus there is a constant need to discover new and efficient treatment against the disease by seeking to uncover various novel alternate signalling...

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Identifiers

PMID: 19997558
DOI: 10.1371/journal.pone.0008100
PMCID: PMC2785475

Genes

EGFR
CAV1
CDH5
GAPDH
PTPN1
SUMO4
TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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