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Article

Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70.

EMBO reports - 1 Jul 2007

Momose Takaki, Ohshima Chié, Maeda Masahiro, Endo Toshiya

Abstract excerpt

Mitochondrial heat-shock protein 70 (mtHsp70) and its partner proteins drive protein import into the matrix. Tim15/Zim17/Hep1 is a mtHsp70 partner protein on the matrix side of the inner mitochondrial membrane. We determined the nuclear magnetic resonance (NMR) structure of the core domain of Tim15. On the basis of the NMR structure, we created Tim15 mutants and tested their ability to complement the functional...

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Identifiers

PMID: 17571076
DOI: 10.1038/sj.embor.7400990
PMCID: PMC1905897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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