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Article

Effectiveness of vaccinationwith recombinant HpaA from<i>Helicobacter pylori</i>is influenced by host genetic background

25 Jan 2007

Abstract excerpt

Several studies have explored the production and immunogenicity of HpaA as a potential protective antigen against Helicobacter pylori but little is known regarding its protective capabilities. We therefore evaluated the protective efficacy of recombinant HpaA (rHpaA) as a candidate vaccine antigen against H. pylori. To explore the impact of genetic diversity, inbred and outbred mice were prophylactically and...

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PMID: 17567282
DOI: 10.1111/j.1574-695x.2006.00206.x

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