Article
Genomic and vaccine preclinical studies reveal a novel mouse-adapted Helicobacter pylori model for the hpEastAsia genotype in Southeast Asia.
Journal of medical microbiology - 1 Jan 2024
Nguyen Thi Kim Cuc, Do Hoang Dang Khoa, Nguyen Thi Lan Phuong, Pham Thu Thuy, Mach Bao Ngoc, Nguyen Thi Chinh, Pham Thi Lan, Katsande Paidamoyo M, Hong Huynh Anh, Duong Huu Thai, Phan Anh N, Cutting Simon M, Vu Minh Thiet, Nguyen Van Duy
Abstract excerpt
Introduction. Helicobacter pylori infection is a major global health concern, linked to the development of various gastrointestinal diseases, including gastric cancer. To study the pathogenesis of H. pylori and develop effective intervention strategies, appropriate animal pathogen models that closely mimic human infection are essential.Gap statement. This study focuses on the understudied hpEastAsia genotype in...
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