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Article

HpaA is essential for Helicobacter pylori colonization in mice.

Infection and immunity - 1 Feb 2006

Carlsohn Elisabet, Nyström Johanna, Bölin Ingrid, Nilsson Carol L, Svennerholm Ann-Mari

Abstract excerpt

Infection with the human gastric pathogen Helicobacter pylori can give rise to chronic gastritis, peptic ulcer, and gastric cancer. All H. pylori strains express the surface-localized protein HpaA, a promising candidate for a vaccine against H. pylori infection. To study the physiological importance of HpaA, a mutation of the hpaA gene was introduced into a mouse-adapted H. pylori strain. To justify that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16428735
DOI: 10.1128/IAI.74.2.920-926.2006
PMCID: PMC1360314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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