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Article

Cell Cycle-Related Kinase: A Novel Candidate Oncogene in Human Glioblastoma

12 Jun 2007

Abstract excerpt

BACKGROUND: Median survival for patients with glioblastoma multiforme, the most aggressive glioma, is only 12-15 months, despite multimodal treatment that includes surgery, chemotherapy, and radiotherapy. Thus, identification of genes that control the progression of glioblastoma multiforme is crucial for devising new therapies. We investigated the involvement of cell cycle-related kinase (CCRK), a novel protein...

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PMID: 17565152
DOI: 10.1093/jnci/djm011

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