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Article

MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

1 Dec 2018

Abstract excerpt

BACKGROUND: MicroRNAs play crucial roles in tumorigenesis and tumor progression. miR-770 has been reported to be downregulated in several cancers and affects cancer cell proliferation, apoptosis, metastasis and drug resistance. However, the role and underlying molecular mechanism of miR-770 in human glioma remain unknown and need to be further elucidated. METHODS: The expression of miR-770 in glioma tissues and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30524203
DOI: 10.1186/s12935-018-0694-9

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