Article
Directing neurotransmitter identity of neurones derived from expanded adult neural stem cells.
The European journal of neuroscience - 1 May 2007
Berninger Benedikt, Guillemot François, Götz Magdalena
Abstract excerpt
In-vitro expanded neural stem cells (NSCs) of the adult subependymal zone (SEZ) may serve as a source for replacing degenerating neurones in disease and trauma. Crucial for the viability of this approach is the ability to selectively generate specific types of neurones from these cells. Here we show that NSCs derived from the adult mouse SEZ and expanded in vitro as neurosphere cells lose their in-vivo...
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