Article
No association between the tumor necrosis factor-alpha gene promoter polymorphisms and schizophrenia in a Japanese population.
Psychiatry research - 30 Sept 2007
Watanabe Yuichiro, Muratake Tatsuyuki, Kaneko Naoshi, Fukui Naoki, Nara Yasushi, Someya Toshiyuki
Abstract excerpt
Tumor necrosis factor-alpha (TNF-alpha) is a pleiotrophic cytokine and exerts neuroprotective and neurodegenerative effects in brain. Several studies have indicated that TNF-alpha is likely related to the pathogenesis of schizophrenia. Recent genetic investigations have revealed that a TNF-alpha gene promoter polymorphism (-G308A) is associated with schizophrenia, although negative findings have also been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
