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Article

No association between the G308A polymorphism of the tumor necrosis factor-alpha gene and schizophrenia.

European archives of psychiatry and clinical neuroscience - 1 Oct 2002

Riedel Michael, Krönig Holger, Schwarz Markus J, Engel Rolf R, Kühn Kai-Uwe, Sikorski Christopher, Sokullu Safet, Ackenheil Manfred, Möller Hans-Jürgen, Müller Norbert

Abstract excerpt

Several linkage analyses in schizophrenia research point to a locus on chromosome 6p22, where the gene coding for tumor necrosis factor-alpha (TNF-alpha) is located. A marked influence of antipsychotic medication on TNF-alpha has been described. As the involvement of an immune process in the pathophysiology of schizophrenia has been discussed, a functional TNF-alpha polymorphism appears to be a candidate in...

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PMID: 12451465
DOI: 10.1007/s00406-002-0386-1

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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