Article
Tumor necrosis factor-alpha --G308A polymorphism in schizophrenia in a Finnish population.
Neuroscience letters - 2 Sept 2005
Hänninen Kari, Katila Heikki, Rontu Riikka, Mattila Kari M, Hurme Mikko, Lehtimäki Terho
Abstract excerpt
Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine with functions in nerve cell growth, differentiation, and apoptosis. There are several studies showing that a TNF-alpha--G308A promoter polymorphism, which possibly affects TNF-alpha transcription, is associated with schizophrenia, although negative results also exist. Our aim was to investigate the relationship between the TNF-alpha --G308A...
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