Article
Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility.
Journal of gastroenterology and hepatology - 1 Dec 2007
Frances Carmen P, Conde Manuel C, Saez Maria E, Diez Servando F, Rey Concha M, Ramírez-Armengol Juan A, Pascual Manuel H, Gonzalez-Perez Antonio, Torres Pablo P, Real Luis M, Serrano-Rios Manuel, López José L G, Ruiz Agustin, Royo Jose L
Abstract excerpt
BACKGROUND AND AIM: Colorectal cancer (CRC) is one of the most prevalent types of cancer affecting both men and women in developed countries. Clinical and molecular evidence suggests that there are multiple biochemical pathways involved in its susceptibility, pathogenesis and prognosis. Several studies have reported a significant association between the incidence of CRC and type 2 diabetes mellitus (T2DM)....
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