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Antigen‐specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis

11 Jun 2007

Abstract excerpt

Infection with West Nile virus (WNV) causes fatal encephalitis in immunocompromised animals. Previous studies in mice have established that T cell protection is required for clearance of WNV infection from tissues and preventing viral persistence. The current study assessed whether specific WNV peptide epitopes could elicit a cytotoxic T lymphocyte (CTL) response capable of protecting against virus infection....

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PMID: 17559174
DOI: 10.1002/eji.200737192

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